Spurs go into the game having won nine consecutive league matches for the first time since 1960, when they won 13 in a row.
And they’ve got a good record against West Ham too, with the Hammers winning only five of their last 20 meetings in all competitions.
However, Slaven Bilić’s side could go unbeaten in five consecutive league games for the first team this season if they avoid defeat.
NOW PROVE YOUR FOOTBALL KNOWLEDGE BY CREATING AND SHARING YOUR OWN STARTING XI FOR WEST HAM vs TOTTENHAM
Tottenham came through their game against Arsenal unscathed and those missing out are only-long term absentees.
There was talk of Danny Rose returning for the North London derby, but he wasn’t on the bench. Rose won’t reportedly start full first-team training until next week, so he’s unlikely to be involved, meaning Ben Davies is likely to carry on in the team.
He favoured the latter against the Gunners, which has led to much speculation about Walker’s future – but who he chooses may depend on the formation he picks.
Mousa Dembélé could return to the starting line-up too after being left out of the game against Arsenal as a precaution.
Who would you pick if you were Pochettino? Let us know.