While a favourable draw compared to Chelsea and Tottenham Hotspur, United will be fully aware of what the Spanish side can do after watching them come back from a 3-0 deficit to draw 3-3 against Liverpool in the group stage.
Our unique algorithm has predicted the United side it believes will start the game.
Football Whispers uses data to predict teams’ starting XIs, taking into account injuries, suspensions, the statistical likelihood of a player being selected, the competition the match is in, players’ previous performances and the opponent’s style.
And you can also give it a go yourself. Just click ‘create your own’ on the line-up at the top of the page and pick your ideal XI for the game.You can also see each player’s stats once you’ve selected them.
When you’re happy with your team, press ‘confirm’ and you’ll be able to share it with your friends via social media.