The Magpies have won just one of their last five top flight games and sit two points above the drop zone. However, victory against the Saints, who are just one place and one point behind Rafa Benitez’s side, would greatly boost their chances of avoiding relegation.
And there is no doubt the Newcastle boss will be carefully plotting a way past Mauricio Pellegrino’s men. But who should be start?
Our unique algorithm has predicted the Toon side it believes will start the game.
Football Whispers uses data to predict teams’ starting XIs, taking into account injuries, suspensions, the statistical likelihood of a player being selected, the competition the match is in, players’ previous performances and the opponent’s style.
And you can also give it a go yourself. Just click ‘create your own’ on the line-up at the top of the page and pick your ideal XI for the game.You can also see each player’s stats once you’ve selected them.
When you’re happy with your team, press confirm and you’ll be able to share it with your friends via social media.